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Table 2 Pagetoid spread in the epidermis

From: Prostate carcinoma metastatic to the skin as an extrammamary Paget’s disease

A. PRIMARY NEOPLASMS

Paget’s Disease (PD)[17]

• Primary PD

• De novo in the areola[18]

Melanocytic Tumors[19]

• Malignant melanoma[20]

• Spitz’s nevus[21]

• Acral nevus[22]

Epithelial Cutaneous Neoplasms

• Squamous cell carcinoma (Bowen’s disease)[23]

• Extraocular sebaceous carcinoma of the shoulder[24] and left upper arm[25]

• Ocular sebaceous carcinoma (of Meibomian gland origin) in eyelids[26, 27]

• Merkel cell carcinoma[28]

• Tricholemmal carcinoma[29]

• Porocarcinoma[30]

• Basal cell carcinoma[31]

Benign Epidermal Conditions

• Focal acantholytic dyskeratosis[32]

• Cutaneous hamartoma with pagetoid cells[33]

• Clear cell papulosis of the skin[34, 35]

• Pagetoid dyskeratosis of the prepuce[36]

• Benign mucinous metaplasia of the penis (mucosal side of prepuce)[37]

• Mammary gland-related clear cells of normal nipples (Toker cells)[38, 39]

Lymphohematopoietic Conditions

• Cutaneous T-cell lymphoma

• Pagetoid reticulosis

• Localized Woringer-Kolopp disease[40]

• and generalized Ketron-Goodman disease[41]

• Mycosis fungoides, common type

• Langerhans cell histiocytosis: self-healing[42], malignant[43], nodular[44]

• Leukemia: Monoblastic leukemia[45]

B. METASTATIC NEOPLASMS

Carcinomas and Malignant Melanoma