Figure 1

Histological features of the spleen. Images of the H&E stained spleen sections at 20x (A), 100x (B) and 400x (C, D) magnification showing expansion of the white pulp nodules and significant infiltration of the red pulp by small mature lymphocytes with minimal cytologic atypia. Occasional binucleated lymphocytes are noted in the splenic sinusoids indicated by black arrows (C, D and D inset).