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Figure 2 | Diagnostic Pathology

Figure 2

From: Histological and immunohistochemical features of the spleen in persistent polyclonal B-cell lymphocytosis closely mimic splenic B-cell lymphoma

Figure 2

Immunohistochemical features of the spleen. Only few scattered T lymphocytes are seen as highlighted by CD3 stain (A, magnification 100x). Majority of lymphocytes in the white and red pulp are CD20 positive (B, magnification 100x) and BCL-2 positive (C, magnification 200x) B cells. PCR for IgH gene rearrangement performed on spleen paraffin-embedded sections reveals polyclonal pattern with no clonal rearrangements detected (D) (Lane 1 - no DNA; Lane 2 - patient; Lane 3 - negative control; Lane 4 - positive control).

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