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Table 2 Specimen information

From: Comparison of histopathology to gene expression profiling for the diagnosis of metastatic cancer

Case

Gender *, **

Primary site

Biopsy site

Description*

1

Female

Ovary

Omentum

This specimen received labeled with patient’s name are two, pink-yellow, lobulated omental tissue fragments measuring 14.5 × 7.0 × 1.0 cm in aggregate. Sectioning omentum reveals yellow lobulated adipose tissue marked by multiple, firm, yellow-white nodule varying in size from 0.5 × 0.5 × 0.5 cm. up to 2.0 × 1.5 × 1.0 cm. Some of these nodules show focal hemorrhage and necrosis. Representative sections are submitted in cassette. Two pieces.

2

Male

Colorectal

Liver

The specimen consists of a 360 gram, 16.5 × 7.0 × 7.0 cm segment of liver. The superior portion of the liver has been inked yellow, and the resection margin has been inked black. The liver has a pink-tan appearance with adhesions. Previous sectioning revealed a 2.5 × 2.5 cm white-tan nodule located approximately 6.0 cm from the superior portion of the liver and comes to within 1.0 cm from the resection margin. Located approximately 1.5 cm inferior to the first nodule are 2 additional white-tan, circumscribed nodules. These measure 0.2 cm and 1.3 cm in greatest dimension. The larger nodule comes to within 0.5 cm from the resection margin, and the smaller nodule comes to within 2.2 cm from the resection margin. The remaining liver has a green-brown appearance, and no additional areas of interest are identified. Second and third nodules are submitted in one cassette, 1 piece.

3

Male

Colorectal

Brain

Specimen received labeled with right frontal brain tumor. Received is a 3.0 × 2.1 × 0.3 cm aggregate of gray-tan, friable tissue fragments. Tea bag. 1 cassette, all.

4

Female

Breast

Lymph Node

This specimen received labeled with patient’s name. Contains 1 possible lymph node, 1 piece.

5

Male

Kidney

Brain

The specimen consists of a previously sectioned portion of red-gray brain tissue which upon reconstruction measures 4.0 × 3.1 × 2.0 cm. There is a 3.5 × 2.0 × 1.1 cm ill-defined yellow-gray mass which comes to within 0.3 cm of the margin. The margin has been inked black. The remaining cut surface is gray-pink, and no additional masses or areas of interest are grossly identified. Representative tissue is submitted in 1 cassette, 1 piece.

6

Female

Melanoma

Lymph Node

Possible lymph nodes, 1 cassette, multiple pieces.

7

Male

Bladder

Lymph Node

The specimen received consists of multiple fragments of fat and soft connective tissue. On sectioning, the fragments consist of possible lymph nodes ranging from 0.7 cm up to 4.3 cm in greatest dimension. The cut surfaces are solid gray-white. Possible lymph nodes, multiple pieces.

8

Male

Sarcoma

Liver

Received is a 1765 gram, 20.7 × 14.3 × 10.8 cm right lobe of liver. There is a stitch attached to the anterior aspect of the capsule. The resection margin will be inked black. On sectioning, there is a 10.4 × 6.8 cm white-tan, fleshy, friable mass. The mass is focally necrotic and in the area where the mass is necrotic, it is cystic. The mass grossly appears to come to within 1.1 cm of the resection margin. The remaining liver is red-brown and no satellite lesions or other masses are grossly identified. 1 cassette, 1 piece.

9

Male

Gastric

Omentum

The specimen consists of a 0.9 × 0.7 × 0.5 cm portion of yellow, lobulated omentum with a 1.2 cm firm, gray nodule. 1 cassette, 1 piece.

10

Male

Lung

Brain

The specimen consists of a 1.6 × 1.3 × 0.7 cm aggregate of soft tan-brown tissue fragments. Submitted in 1 cassette, multiple pieces.

  1. * - Information given to EPs.
  2. ** - Information given for GEP testing to Pathwork Diagnostics Laboratory.