Table 5 Diagnoses provided by evaluating pathologists and GEP test vs. the reference diagnosis
From: Comparison of histopathology to gene expression profiling for the diagnosis of metastatic cancer
Case No. | Reference Diagnosis | Sex | GEP | EP1 | EP2 | EP3 | EP4 | EP5 | EP Overall, for 50 case reviews | ||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Result | Highest SS | H&E | Int | Final | All | H&E | Int | Final | All | H&E | Int | Final | All | H&E | Int | Final | All | H&E | Int | Final | All | H&E | Int | All | |||
Case 1 | OV | F | OV | 97.6 | BR | OV | OV | OV | OV | OV | OV | OV | OV | OV | OV | OV | OV | OV | OV | OV | OV | -- | -- | -- | |||
Case 2 | CO | M | CO | 89.9 | CO | CO | CO | CO | CO | CO | CO | CO | CO | PA | PA | PA | CO | LU | LU | LU | -- | -- | -- | ||||
Case 3 | CO | M | CO | 87.6 | CO | CO | CO | CO | CO | CO | CO | CO | CO | LU | CO | CO | CO | CO | CO | CO | -- | -- | -- | ||||
Case 4 | BR | F | BR | 97.6 | LU | OV | OV | OV | LU | LU | LU | BR | BR | PA | PA | OV | OV | PA | PA | OV | OV | OV | OV | -- | -- | -- | |
Case 5 | KI | M | KI | 86.4 | KI | KI | KI | KI | KI | KI | KI | KI | KI | LU | KI | KI | KI | KI | KI | KI | -- | -- | -- | ||||
Case 6 | ME | F | ME | 67.4 | LY | ME | ME | ME | BR | BR | BR | LI | ME | ME | ME | BR | ME | ME | ME | LU | ME | ME | ME | -- | -- | -- | |
Case 7 | BL | M | BL | 45.1 | GC | PA | BL | LU | GA | GA | LU | LU | BL | BL | LU | BL | BL | BR | BL | PA | PA | -- | -- | -- | |||
Case 8 | SC | M | SC | 76.1 | SC | SC | SC | LI | SC | SC | SC | SC | SC | SC | LI | ME | ME | KI | LI | LI | LI | -- | -- | -- | |||
Case 9 | GA | M | GA | 36.9 | GA | GA | GA | SC | GA | GA | GA | GA | GA | GA | GA | PA | PA | PA | LY | GA | GA | GA | -- | -- | -- | ||
Case 10 | LU | M | OV | 24.4 | BL | BL | BL | BL | BL | BL | BL | BL | BL | BL | BL | BL | BL | BL | BL | BL | BL | -- | -- | -- | |||
No. incorrect | 1 | 5 | 3 | 2 | 6 | 4 | 4 | 3 | 2 | 2 | 9 | 5 | 5 | 6 | 4 | 5 | 5 | 29 | 19 | 18 | |||||||
No. correct | 9 | 5 | 7 | 8 | 4 | 6 | 6 | 7 | 8 | 8 | 1 | 5 | 5 | 4 | 6 | 5 | 5 | 21 | 31 | 32 | |||||||
% correct | 90% | 50% | 70% | 80% | 40% | 60% | 60% | 70% | 80% | 80% | 10% | 50% | 50% | 40% | 60% | 50% | 50% | 42% | 62% | 64% | |||||||