Apoptosis signal-regulating kinase 1 is associated with the effect of claudin-6 in breast cancer

Diagnostic Pathology

Table 1 Clinicopathological features and the expression of ASK1 in 85 IDC samples

Clinicopathological features	Cases	ASK1 expression (n)		χ 2	P
		Positive	Negative
Age (years)				0.017	0.896
≥45	58	18	40
<45	27	8	19
Histological grade				0.668	0.414
I ~ II	21	8	13
III	63	18	45
Tumor size				0.21	0.646
≥5 cm³	66	21	45
<5 cm³	19	5	14
Lymph node metastasis				0.527	0.468
Positive	41	11	30
Negative	44	15	29
TNM stage				0.336	0.562
I,II	55	18	37
III,IV	30	8	22
Lesion location				2.406	0.121
Right	45	10	35
Left	34	13	21
ER				0.105	0.746
Positive	37	12	25
Negative	48	14	34
PR				0.425	0.515
Positive	38	13	25
Negative	47	13	34
C-erb B-2				5.747	0.017
Positive	27	13	14
Negative	58	13	45