From: Apoptosis signal-regulating kinase 1 is associated with the effect of claudin-6 in breast cancer
Clinicopathological features | Cases | ASK1 expression (n) | χ 2 | P | |
---|---|---|---|---|---|
 |  | Positive | Negative |  |  |
Age (years) | Â | Â | Â | 0.017 | 0.896 |
 ≥45 | 58 | 18 | 40 | ||
 <45 | 27 | 8 | 19 | ||
Histological grade | Â | Â | Â | 0.668 | 0.414 |
 I ~ II | 21 | 8 | 13 | ||
 III | 63 | 18 | 45 | ||
Tumor size | Â | Â | Â | 0.21 | 0.646 |
 ≥5 cm3 | 66 | 21 | 45 | ||
 <5 cm3 | 19 | 5 | 14 | ||
Lymph node metastasis | Â | Â | Â | 0.527 | 0.468 |
 Positive | 41 | 11 | 30 | ||
 Negative | 44 | 15 | 29 | ||
TNM stage | Â | Â | Â | 0.336 | 0.562 |
 I,II | 55 | 18 | 37 | ||
 III,IV | 30 | 8 | 22 | ||
Lesion location | Â | Â | Â | 2.406 | 0.121 |
 Right | 45 | 10 | 35 | ||
 Left | 34 | 13 | 21 | ||
ER | Â | Â | Â | 0.105 | 0.746 |
 Positive | 37 | 12 | 25 | ||
 Negative | 48 | 14 | 34 | ||
PR | Â | Â | Â | 0.425 | 0.515 |
 Positive | 38 | 13 | 25 | ||
 Negative | 47 | 13 | 34 | ||
C-erb B-2 | Â | Â | Â | 5.747 | 0.017 |
 Positive | 27 | 13 | 14 |  |  |
 Negative | 58 | 13 | 45 |  |  |