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Table 2 Immunohistochemical staining scores of benign, borderline and malignant ovarian tumors

From: Immunohistochemistry with apoptotic-antiapoptotic proteins (p53, p21, bax, bcl-2), c-kit, telomerase, and metallothionein as a diagnostic aid in benign, borderline, and malignant serous and mucinous ovarian tumors

 

Benign (n = 25)

Borderline (n = 16)

Malign (n = 27)

Significance

p53 *

0 (0–0)

0.5 (0–3)

4 (0–4)

p < 0.05

p21 *

1 (0–4)

3.5 (1–4)

4 (1–4)

p = 0.05

bax **

0 (0–2)

1 (0–4)

1 (0–6)

p < 0.05

bcl-2 **

0 (0–2)

0 (0–6)

0 (0–4)

NS

c-kit **

0 (0–6)

0 (0–4)

0 (0–12)

NS

Telomerase*

0 (0–3)

0 (0–3)

0 (0–3)

NS

Metallothionein**

0 (0–9)

3.5 (0–12)

6 (0–12)

p < 0.05

  1. Data were presented as median (min-max).
  2. NS, not significant. *Nuclear staining score. **Quick score.