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Table 2 Immunohistochemical staining scores of benign, borderline and malignant ovarian tumors

From: Immunohistochemistry with apoptotic-antiapoptotic proteins (p53, p21, bax, bcl-2), c-kit, telomerase, and metallothionein as a diagnostic aid in benign, borderline, and malignant serous and mucinous ovarian tumors

  Benign (n = 25) Borderline (n = 16) Malign (n = 27) Significance
p53 * 0 (0–0) 0.5 (0–3) 4 (0–4) p < 0.05
p21 * 1 (0–4) 3.5 (1–4) 4 (1–4) p = 0.05
bax ** 0 (0–2) 1 (0–4) 1 (0–6) p < 0.05
bcl-2 ** 0 (0–2) 0 (0–6) 0 (0–4) NS
c-kit ** 0 (0–6) 0 (0–4) 0 (0–12) NS
Telomerase* 0 (0–3) 0 (0–3) 0 (0–3) NS
Metallothionein** 0 (0–9) 3.5 (0–12) 6 (0–12) p < 0.05
  1. Data were presented as median (min-max).
  2. NS, not significant. *Nuclear staining score. **Quick score.