Genomic amplification of the human telomerase gene (hTERC) associated with human papillomavirus is related to the progression of uterine cervical dysplasia to invasive cancer

Table 1 Summary of hTERC amplification according to histology diagnosis

Histology Dx	Number of cases	No. of cases with hTERC amplification (%)*	Mean of cell number with hTERC amplification
NNL	26	0	1.058
CIN1	19	4 (21.1%)	5.132
CIN2	12	6 (50%)	6.083
CIN3	27	22 (81.5%)	11.093
CA	19	19 (100%)	21.105

Dx, diagnosis; NNL, non neoplastic lesion; CIN, cervical intraepithial neoplasia; CA, cervical carcinoma.
*A case of hTERC amplification was defined as more than 5.8% of the cells showed a pattern when number of hTERC signal was more than 2.

ISSN: 1746-1596