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Table 3 Immunohistochemical expression of arginase-1 and HepPar-1 according to the pattern of staining in all positive cases

From: The diagnostic value of arginase-1 immunostaining in differentiating hepatocellular carcinoma from metastatic carcinoma and cholangiocarcinoma as compared to HepPar-1

 

Arginase-1

HepPar-1

Focal No (%)

Diffuse No (%)

Total positive

Focal No (%)

Diffuse No (%)

Total positive

Hepatocellular carcinoma (HCC), (no=50):

10 (23.8)

32 (76.2)

42

15 (42.9)

20 (57.1)

35

well differentiated (no=11)

0 (0)

11 (100)

11

1 (9.1)

10 (90.9)

11

moderately differentiated (no=30)

8 (29.6)

19 (70.4)

27

10 (33.3)

12 (40)

22

poorly differentiated (no=9)

2 (50)

2 (50)

4

2 (22.2)

0 (0)

2

Metastatic carcinoma (MC) (no=38):

1 (100)

0 (0)

1

1 (16.7)

5 (83.3)

6

Colonic (no=25)

(0)

0 (0)

0

1 (33.3)

2 (66.7)

3

Gastric (no=6)

0 (0)

0 (0)

0

0 (0)

3 (100)

3

Renal cell carcinoma (no=2)

0 (0)

0 (0)

0

0 (0)

0 (0)

0

Pancreas (no=2)

1 (100)

0 (0)

1

0 (0)

0 (0)

0

Lung (no=2)

0 (0)

0 (0)

0

0 (0)

0 (0)

0

Gall bladder (no=1)

0 (0)

0 (0)

0

0 (0)

0 (0)

0

Cholangiocarcinoma (no=12)

1 (100)

0 (0)

1

1 (50)

1 (50)

2

Non-neoplastic cirrhotic liver tissues adjacent to HCC(no=42)

0 (0)

42 (100)

42

0 (0)

42 (100)

42

Non-neoplastic liver tissue adjacent to MC (no= 9)

0 (0)

9 (100)

9

0 (0)

9 (100)

9

Normal liver tissues (no=10)

0 (0)

10 (100)

10

0 (0)

10 (100)

10

  1. HepPar-1=hepatocyte paraffin antigen-1.