Figure 1

Immunohystochemical staining reaction of LGALS3BP, RAD50, and FAM50A MBC-associated antigens in breast cancer and non-cancerous tissues. Cancer cells of MBC and IDC demonstrated moderate to strong cytoplasmic and weak nuclear LGALS3BP staining, while in ILC samples weak cytoplasmic and moderate nuclear staining was observed. Strong positive LGALS3BP staining of cytoplasm and the apical part of normal epithelial cells was detected. Predominantly strong (3+) nuclear RAD50 staining in normal and cancer cells of MBC, IDC, and ILC was detected. Antigen FAM50A had moderate nuclear and weak cytoplasmic staining in NCT and tumor samples. C – cancer cells, L – lymphocytic infiltrate. Magnification 400x