Figure 2

Immunohystochemical staining reaction of RBPJ, PABPC4, and LRRFIP1 MBC-associated antigens in breast cancer and non-cancerous tissues. Antigen RBPJ had moderate nuclear and weak cytoplasmic staining of normal and cancer cells of NCT, MBC, and IDC, except for ILC samples which showed only moderate (2+) nuclear staining. Moderate to strong positive PABPC4 staining was detected in cytoplasm of normal and cancer cells of non-cancerous and cancer tissue samples. Cancer cells of IDC and ILC, and normal cells of non-cancerous tissues had moderate to strong nuclear and weak cytoplasmic LRRFIP1 staining, but in MBC moderate cytoplasmic LRRFIP1 staining was observed. C – cancer cells, L – lymphocytic infiltrate. Magnification 400x