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Table 6 Associations between the factor scores and the conventional categories of the hormone receptor positive ductal carcinoma of the breast

From: Immunohistochemistry profiles of breast ductal carcinoma: factor analysis of digital image analysis data

 

n

i-IHC-High

SATB1-High

HER2-High

p53-High

p16-High

Number of patients

85

     

Age group

 

n.s.

p < 0.0015

n.s.

p < 0.003

n.s.

Age < 55 year

39

12 (31)

12 (31)

22 (56)

30 (77)

20 (51)

Age > 55 year

46

12 (26)

30 (65)

18 (39)

21 (46)

25 (54)

Histological grade

 

n.s.

p < 0.2951

p < 0.0001

n.s.

n.s.

1

19

6 (32)

7 (37)

3 (16)

8 (42)

9 (47)

2

38

10 (26)

22 (58)

14 (37)

25 (66)

22 (58)

3

28

8 (29)

13 (46)

23 (82)

18 (64)

14 (50)

T

 

n.s.

n.s.

n.s.

n.s.

n.s.

1

49

13 (27)

28 (57)

22 (45)

32 (65)

23 (47)

2

36

11(31)

14 (39)

18 (50)

19 (53)

22 (61)

N

 

n.s.

n.s.

n.s.

n.s.

n.s.

0

48

14 (29)

23 (48)

23 (48)

28 (58)

25 (52)

1

37

10(27)

19 (51)

17 (46)

23 (62)

20 (54)

Intrinsic subtype

 

n.s.

p < 0.0331

p < 0.0001

n.s.

n.s.

Luminal A

43

13 (30)

19 (44)

7 (16)

21 (49)

22 (51)

Luminal B

27

7(26)

11 (41)

23 (85)

19 (70)

12 (44)

Luminal B HER2+

15

4 (27)

12 (80)

10 (67)

11 (73)

11 (73)