Variables | Number of cases (%) | Claudin-6 | MeCP2 | DNMT1 | ||||||
---|---|---|---|---|---|---|---|---|---|---|
 |  | Positive (%) | Negative (%) | P | Positive (%) | Negative (%) | P | Positive (%) | Negative (%) | P |
Breast invasive ductal carcinoma | 100(100%) | 25(25%) | 75(75%) | < 0.001 | 88(88%) | 12(12%) | < 0.001 | 69(69%) | 31(31%) | 0.001 |
Control | 22(100%) | 20 (91%) | 2 (9%) | Â | 6 (27%) | 16(73%) | Â | 7(32%) | 15(68%) | Â |
Age (year) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
≤ 40 | 20(20%) | 5(25%) | 15(75%) | 1.000 | 16(80%) | 4(20%) | 0.251* | 15(75%) | 5(25%) | 0.060 |
> 40 | 80(80%) | 20(33%) | 60(67%) | Â | 72(90%) | 8(10%) | Â | 73(91%) | 7(9%) | Â |
Tumour size(cm) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
≤ 5 | 91(91%) | 24(26%) | 67(63%) | 0.444* | 80(88%) | 11(12%) | 1.000* | 65(71%) | 26(29%) | 0.131 |
> 5 | 9 (9%) | 1(11%) | 8(89%) | Â | 8(89%) | 1(11%) | Â | 4(44%) | 5(56%) | Â |
Differentiation | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
well | 25(25%) | 9(36%) | 16(64%) | 0.142 | 21(84%) | 4(16%) | 0.488* | 17(68%) | 8(32%) | 0.902 |
poor | 75(75%) | 16(21%) | 59(79%) | Â | 67(89%) | 8(11%) | Â | 50(67%) | 25(33%) | Â |
Clinical stage | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
I | 20(20%) | 5(21%) | 19(79%) | 0.760 | 18(90%) | 2(10%) | 0.074* | 10(50%) | 10(50%) | 0.113 |
II | 46(46%) | 10(22%) | 36(78%) | Â | 37(80%) | 9(20%) | Â | 35(76%) | 11(24%) | Â |
III-IV | 34(34%) | 10(29%) | 24(71%) | Â | 33(97%) | 1(3%) | Â | 23(68%) | 11(32%) | Â |
Lymph node metastasis | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Positive | 48(48%) | 7(15%) | 41(85%) | 0.021 | 43(90%) | 5(10%) | 0.640 | 34(71%) | 14(29%) | 0.972 |
Negative | 52(52%) | 18(35%) | 34(65%) | Â | 45(87%) | 7(13%) | Â | 37(71%) | 15(29%) | Â |