Variables | Number of cases (%) | HDAC1 | H3Ac | H4Ac | ||||||
---|---|---|---|---|---|---|---|---|---|---|
 |  | Positive (%) | Negative (%) | P | Positive (%) | Negative (%) | P | Positive (%) | Negative (%) | P |
Breast invasive ductal carcinoma | 100(100%) | 67(67%) | 33(33%) | Â | 90(90%) | 10(10%) | Â | 79(79%) | 21(21%) | 0.243* |
Control | 22(100%) | 3 (14%) | 19(86%) | < 0.001 | 14(64%) | 8 (36%) | 0.004* | 20(91%) | 2 (9%) | Â |
Age (year) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
≤ 40 | 20(20%) | 8(40%) | 12(60%) | 0.004 | 18(90%) | 2(10%) | 1.000* | 17(85%) | 3(15%) | 0.554* |
> 40 | 80(80%) | 59(74%) | 21(26%) | Â | 72(90%) | 8(10%) | Â | 62(78%) | 18(22%) | Â |
Tumour size(cm) | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
≤ 5 | 91(91%) | 62(68%) | 29(22%) | 0.472* | 84(92%) | 7(8%) | 0.044* | 74(81%) | 17(19%) | 0.089* |
> 5 | 9 (9%) | 5(56%) | 4(44%) | Â | 6(67%) | 3(23%) | Â | 5(56%) | 4(44%) | Â |
Differentiation | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
well | 25(25%) | 8(32%) | 17(68%) | < 0.001 | 24(96%) | 1(4%) | 0.444* | 20(80%) | 5(20%) | 0.887 |
poor | 75(75%) | 59(79%) | 16(21%) | Â | 66(88%) | 9(12%) | Â | 59(79%) | 16(21%) | Â |
Clinical stage | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
I | 20(20%) | 12(60%) | 8(40%) | 0.007 | 17(85%) | 3(15%) | 0.034* | 18(90%) | 2(10%) | 0.227 |
II | 46(46%) | 38(83%) | 8(17%) | Â | 45(98%) | 1(2%) | Â | 37(80%) | 9(20%) | Â |
III-IV | 34(34%) | 17(50%) | 17(50%) | Â | 28(82%) | 6(18%) | Â | 24(71%) | 10(29%) | Â |
Lymph node metastasis | Â | Â | Â | Â | Â | Â | Â | Â | Â | Â |
Positive | 48(48%) | 40(83%) | 8(17%) | 0.001 | 43(90%) | 5(10%) | 1.000* | 37(77%) | 11(23%) | 0.651 |
Negative | 52(52%) | 27(52%) | 25(48%) | Â | 47(90%) | 5(10%) | Â | 42(81%) | 10(19%) | Â |