Figure 2

Axillary lymph node morphology. Effacement of lymph node architecture with burnt-out follicles (A) and marked vascular proliferation (B) was observed. The neoplastic cells show clear-to-pale cytoplasm, distinct cell membrane and minimal atypia (C); they mainly express CD4 (D). EBV-positive B cells are present (inset, D). [A-C: Haematoxylin–Eosin (H&E); Original Magnification (O.M.): 40x; D: CD4 stain, O.M.: 40x; D, inset: EBER in situ hybridization, O.M.: 40x.