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Table 1 Relationship between clinicopathological features and c-MET expression in gastric cancers (n = 124)

From: The clinicopathologic association of c-MET overexpression in Iranian gastric carcinomas; an immunohistochemical study of tissue microarrays

Subjects variables

c-MET expression

P-value

High

Low

(n = 88)

(n = 36)

Age (year)

62.3 ± 12.6

59.5 ±14.4

NS*

Sex

   

Male

72

27

NS

Female

16

9

 

Tumor location

Cardia (upper third)

22

8

NS

Body (middle third)

29

13

 

Antrum (lower third)

30

11

 

Diffuse

7

4

 

Tumor greatest dimension (cm)

5.9 ± 3.1

5.7 ± 3.8

NS

Tumor differentiation

   

Well

11

2

NS

Moderate

32

11

 

Poor

45

23

 

Tumor type

Intestinal

70

21

0.04

Diffuse

14

13

 

Mixed

4

2

 

Depth of invasion

pT1

2

5

0.014

pT2

29

17

 

pT3

54

13

 

pT4

3

1

 

Lymph node metastasis

pN0

14

11

0.065

pN1, 2, 3

74

25

 

Distant metastasis

Present

9

2

NS

Absent

79

34

 

Tumor stage (TNM)

I

9

9

0.044

II

17

11

 

III

48

13

 

IV

14

3

 

Vascular invasion

Present

56

16

0.078

Absent

31

18

 

Unknown

1

2

 

Neural invasion

Present

60

12

0.002

Absent

23

20

 

Unknown

5

4

 
  1. NS = not significant.