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Table 2 The effect of environment on malignant cells

From: Mechanisms of cyst formation in metastatic lymph nodes of head and neck squamous cell carcinoma

Environment

Environmental condition for malignant cells

Proliferation rate

Acquisition of mutations

Tumor presentation

Primary site

Suitable environment

High

High

Low expression of intrinsic properties

Lymph node

Strong immunologic host response, Harsh environment

Low

Low

Silent presentation of tumor and expression of intrinsic properties