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Table 3 IHC descriptive statistics

From: A gene-protein assay for human epidermal growth factor receptor 2 (HER2): brightfield tricolor visualization of HER2 protein, the HER2 gene, and chromosome 17 centromere (CEN17) in formalin-fixed, paraffin-embedded breast cancer tissue sections

  Reader A Reader B Reader C
  Gene-protein IHC (N = 183) Single IHC (N = 183) Gene-protein IHC (N = 183) Single IHC (N = 183) Gene-protein IHC (N = 183) Single IHC (N = 183)
IHC score, n (%)
0 84 (45.9) 90 (49.2) 99 (54.1) 109 (59.6) 110 (60.1) 115 (62.8)
1+ 47 (25.7) 43 (23.5) 34 (18.6) 26 (14.2) 18 (9.8) 14 (7.7)
2+ 10 (5.5) 8 (4.4) 7 (3.8) 6 (3.3) 8 (4.4) 10 (5.5)
3+ 42 (23.0) 42 (23.0) 43 (23.5) 42 (23.0) 47 (25.7) 44 (24.0)
IHC assessment, n (%)
Positive 52 (28.4) 50 (27.3) 50 (27.3) 48 (26.2) 55 (30.1) 54 (29.5)
Negative 131 (71.6) 133 (72.7) 133 (72.7) 135 (73.8) 128 (69.9) 129 (70.5)
  1. IHC: immunohistochemistry.