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Table 3 IHC descriptive statistics

From: A gene-protein assay for human epidermal growth factor receptor 2 (HER2): brightfield tricolor visualization of HER2 protein, the HER2 gene, and chromosome 17 centromere (CEN17) in formalin-fixed, paraffin-embedded breast cancer tissue sections

 

Reader A

Reader B

Reader C

 

Gene-protein IHC (N = 183)

Single IHC (N = 183)

Gene-protein IHC (N = 183)

Single IHC (N = 183)

Gene-protein IHC (N = 183)

Single IHC (N = 183)

IHC score, n (%)

0

84 (45.9)

90 (49.2)

99 (54.1)

109 (59.6)

110 (60.1)

115 (62.8)

1+

47 (25.7)

43 (23.5)

34 (18.6)

26 (14.2)

18 (9.8)

14 (7.7)

2+

10 (5.5)

8 (4.4)

7 (3.8)

6 (3.3)

8 (4.4)

10 (5.5)

3+

42 (23.0)

42 (23.0)

43 (23.5)

42 (23.0)

47 (25.7)

44 (24.0)

IHC assessment, n (%)

Positive

52 (28.4)

50 (27.3)

50 (27.3)

48 (26.2)

55 (30.1)

54 (29.5)

Negative

131 (71.6)

133 (72.7)

133 (72.7)

135 (73.8)

128 (69.9)

129 (70.5)

  1. IHC: immunohistochemistry.