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Figure 1 | Diagnostic Pathology

Figure 1

From: Invasive salivary duct carcinoma ex pleomorphic adenoma of the parotid gland: a teaching case giving rise to the genuine diagnostic difficulty on an inadequate cytology specimen

Figure 1

Cytomorphologic examination of the fine needle aspiration specimens. (A) The cytology specimens were inadequate, but consisted of few small clusters of cohesive and three-dimensional pleomorphic tumor cells in a papillary-like fashion (rt. side), along with flat sheets of benign monomorphic myoepithelial cells (lt. side) (Papanicolaou stains) and a small amount of metachromatic fibromyxoid stroma (inset, Giemsa stains). Bar = 50 μm. (B) At the periphery of these clusters and sheets, there were scattered and tiny malignant tumor cells, having relatively abundant and finely granular cytoplasm. Additionally, the nuclei were hyperchromatic, medium to large in size, pleomorphic, and often had prominent nucleoli. Bar = 10 μm.

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