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Figure 3 | Diagnostic Pathology

Figure 3

From: Delayed apoptosis by neutrophils from COPD patients is associated with altered bak, bcl-xl, and mcl-1 mRNA expression

Figure 3

Correlations between mRNA levels of Bak, Bcl-xl, and Mcl-1 and lung function parameters. COPD patients are represented by solid circles and healthy controls by open circles (Nā€‰=ā€‰47 for each group) Spearman correlation analysis was used to assess associations between variables. (A) Bak mRNA level was positively correlated with lung function. FEV1/FVC%: rā€‰=ā€‰0.72; Pā€‰<ā€‰0.001; FEV1% reference: rā€‰=ā€‰0.70; Pā€‰<ā€‰0.001. (B) Bcl-xl mRNA level was negatively correlated with lung function. FEV1/FVC%: rā€‰=ā€‰-0.82; Pā€‰<ā€‰0.001; FEV1% reference: rā€‰=ā€‰-0.86; Pā€‰<ā€‰0.001. (C) Mcl-1 mRNA level was negatively correlated with lung function. FEV1/FVC%: rā€‰=ā€‰-0.79; Pā€‰<ā€‰0.001; FEV1% reference: rā€‰=ā€‰-0.79; Pā€‰<ā€‰0.001.

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