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Table 4 Variance in preoperative clinicopathological parameters between patients with and without peruneural invasion (PNI)

From: Prediction of pathological and oncological outcomes based on extended prostate biopsy results in patients with prostate cancer receiving radical prostatectomy: a single institution study

 

PNI present

(n = 63)

PNI absent

(n = 61)

Univariate

Multivariate

P value

P value

Adjusted odds ratio (95% CI)

Mean age [years]

63.7 ± 5.0

64.0 ± 5.0

0.894

  

PSA [ng/ml]

9.5 ± 5.9

8.5 ± 8.5

0.104

  

Gleason score at biopsy

7.4 ± 1.1

6.7 ± 0.9

<0.001

0.001

1.983 (1.342-2.929)

cT stage (n)

  

0.615

  

T1c

49 (77.8%)

50 (82.0%)

   

T2

9 (14.3%)

9 (14.8%)

   

T3a

5 (7.9%)

2 (3.3%)

   

%positive cores

23.5 ± 18.7

19.8 ±14.8

0.513

  

TZ biopsy positive (n)

24 (38.1%)

18 (29.5%)

0.312

  

Number of apex-positive (2–4/0–1) (n)

14/49

15/46

0.755

  

Number of middle-positive (2–4/0–1) (n)

21/42

13/48

0.134

  

Number of base-positive (2–4/0–1) (n)

17/46

10/51

0.153

  
  1. PSA, prostate-specific antigen; TZ, transition zone; apex, prostatic apex biopsy; middle, prostatic middle biopsy; base, prostatic base biopsy.