Table 5 Cox proportional hazard model for recurrence or/and metastasis

Age (y)

0.98 (0.95-1.02)

1.00 (0.97-1.04)

Lymph node ratio^†

1.06 (1.02-1.11)*

-

Gender

 Female

Reference

Reference

 Male

1.75 (0.55-5.58)

2.19 (0.59-8.20)

Location of tumor

 Colon

Reference

-

 Rectum

1.16 (0.40-3.30)

-

Depth of invasion

 T1 or T2

Reference

-

 T3

2.23 (0.47-10.51)

-

 T4

1.03 (0.19-5.63)

-

Stage

 I

Reference

-

 II

0.83 (0.09-8.02)

-

 III

4.60 (0.59-36.07)

-

Tumor grade

 I

Reference

-

 II

0.95 (0.12-7.41)

-

 III

0.69 (0.06-7.67)

-

Upstage

 N0(i+)

9.97 (1.40-71.07)*

8.07 (1.09-59.50)*

 N0

Reference

Reference

 N+

9.67 (2.10-44.47)*

7.87 (1.68-36.79)*

HE examination

 Negative

 Positive

5.93 (1.84-19.12)*

SLN examination

 Negative

 Positive

1.11 (0.25-4.96)