Immunohistochemical characterization of neoplastic cells of breast origin

Diagnostic Pathology

Table 2 Statistical results for each marker

Marker	TP	TN	FP	FN	S (%)	Sp (%)	PPV (%)	+LR	−LR
MAG	10	40	2	19	34	95	83	7.24	0.69
GCDFP-15	13	38	4	16	45	90	76	4.71	0.61
HR	20	41	1	9	69	98	95	29.0	0.32
CK7	25	23	19	4	86	55	57	1.91	0.25

MAG: mammaglobin; GCDFP-15: gross cystic disease fluid protein; HR: estrogen and progesterone receptors; CK7: cytokeratin 7; TP: true positives; TN: true negatives; FP: false positive; FN: false negative; S: sensitivity; Sp: specificity; PPV: positive predictive value; + LR: positive likelihood ratio; − LR: negative likelihood ratio.

ISSN: 1746-1596