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Table 2 Summary of methyaltion conditions and immunoreactivity of 18 patients with primary and recurrent gliomas

From: Concurrent hypermethylation of DNMT1, MGMT and EGFR genes in progression of gliomas

Cases HT DNMT EGFR MGMT
   PGL RGL PGL RGL PGL RGL
1 A2 → A3
2 A2 → A3 - -
3 A3 → A3 - -
4 A2 → A3 - - - -
5 A2 → A3 + - -
6 A2 → A3
7 A3 → GB - - - - - -
8 A3 → GB - - - - - -
9 A3 → GB - - -
10 A3 → GB - - - - - -
11 GB → GB - - - -
12 GB → GB - - - - - -
13 GB → GB - - -
14 GB → GB - - - -
15 GB → GB - -
16 GB → GB - -
17 GCGB → GCGB
18 GCGB → GCGB
  1. Abbreviations: no mark, hypermethylation; oval mark, unmethylation; PGL, primary glioma; RGL, recurrent glioma;HT, histological tranformation; A2, diffuse astrocytoma; A3, anaplastic astrocytoma; GB, glioblastoma; GCGB, giant cell glioblastoma; + positive immunoreactivity; - negative immunoreactivity