Figure 1From: High MCM3 expression is an independent biomarker of poor prognosis and correlates with reduced RBM3 expression in a prospective cohort of malignant melanomaDistribution and sample immunohistochemical images of MCM3 expression in primary and metastatic melanoma. Distribution of immunohistochemical MCM3 expression denoted as the multiplier of fraction and intensity of staining (nuclear score = NS) in a) primary melanoma and b) metastases. Sample images of MCM3 expression in primary tumour and paired metachronous metastasis: c) nodular melanoma on left ear (NS = 2) and d) lymph node metastasis in left groin (NS = 0); e) superficial spreading melanoma on lower left leg (NS = 6) and g) cutaneous metastasis on back of neck (NS = 4); nodular melanoma on lower right leg (NS = 6) and cutaneous metastasis on lower right leg (NS = 9).Back to article page