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Figure 3 | Diagnostic Pathology

Figure 3

From: Analysis of aberrant methylation on promoter sequences of tumor suppressor genes and total DNA in sputum samples: a promising tool for early detection of COPD and lung cancer in smokers

Figure 3

Representative analysis of methylation promoter frequency from sputum samples from CTR, COPD and LC subjects. Methylation promoter frequency (%) for p16, CDH1 and MGMT in COPD and LC group, both compared with CTR group. Group differences were assessed using Fisher’s test. ** P < 0.0001 respect to control group (CTR). * P < 0.05 respect to control group (CTR).

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Diagnostic Pathology

ISSN: 1746-1596

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