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Table 3 Expression of CK7, CK20, and CDX2 in cancer tissues by histopathological characteristics

From: The value of CDX2 and cytokeratins 7 and 20 expression in differentiating colorectal adenocarcinomas from extraintestinal gastrointestinal adenocarcinomas: cytokeratin 7-/20+ phenotype is more specific than CDX2 antibody

 

CK7+

CK20+

CDX2+

 

n

%

n

%

n

%

Colorectal adenocarcinoma (n = 118)

      

   Low grade (n = 96)

22

22.9

87

90.6 *

94

97.9

   High grade (n = 22)

4

18.2

12

54.5 *

20

90.9

   Rectal (n = 85)

18

21.2

76

89.4§

83

97.6

   Nonrectal (n = 33)

8

24.2

23

69.7§

31

93.9

Gastric adenocarcinoma (n = 59)

      

   Intestinal type (n = 30)

21

70.0

16

53.3

23

76.7 #

   Diffuse type (n = 29)

26

89.7

15

51.7

13

44.8 #

Pancreatic adenocarcinoma (n = 32)

      

   Low grade (n = 30)

30

100.0

7

23.3

5

16.7

   High grade (n = 2)

1

50.0

0

0.0

0

0.0

  1. * p < 0.001 § p = 0.009 # p = 0.012