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Table 3 Expression of CK7, CK20, and CDX2 in cancer tissues by histopathological characteristics

From: The value of CDX2 and cytokeratins 7 and 20 expression in differentiating colorectal adenocarcinomas from extraintestinal gastrointestinal adenocarcinomas: cytokeratin 7-/20+ phenotype is more specific than CDX2 antibody

  CK7+ CK20+ CDX2+
  n % n % n %
Colorectal adenocarcinoma (n = 118)       
   Low grade (n = 96) 22 22.9 87 90.6 * 94 97.9
   High grade (n = 22) 4 18.2 12 54.5 * 20 90.9
   Rectal (n = 85) 18 21.2 76 89.4§ 83 97.6
   Nonrectal (n = 33) 8 24.2 23 69.7§ 31 93.9
Gastric adenocarcinoma (n = 59)       
   Intestinal type (n = 30) 21 70.0 16 53.3 23 76.7 #
   Diffuse type (n = 29) 26 89.7 15 51.7 13 44.8 #
Pancreatic adenocarcinoma (n = 32)       
   Low grade (n = 30) 30 100.0 7 23.3 5 16.7
   High grade (n = 2) 1 50.0 0 0.0 0 0.0
  1. * p < 0.001 § p = 0.009 # p = 0.012