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Table 4 Diagnostic odds ratio (dOR) calculated for each immunohistochemistry marker or combination

From: Expression of ck-19, galectin-3 and hbme-1 in the differentiation of thyroid lesions: systematic review and diagnostic meta-analysis

IHC ANALYSIS

dOR (95% CI)

Q

P

CK-19[10, 14–33]

14.73 (8.20-26.45)

110.05

<0.00001

GAL-3[10, 14–17, 19, 21, 25–56]

23.41 (14.02-39.07)

252.72

<0.00001

HBME-1[10, 14–19, 21, 24–27, 29, 30, 41, 51, 57–61]

40.97 (21.42-78.37)

140.82

<0.00001

CK-19 + HBME-1[14, 17]

119.06 (6.81-2080.37)

2.62

0.1058

GAL-3 + CK-19[14, 17]

86.54 (10.8-693.52)

2.89

0.8292

GAL-3 + HBME-1[14, 17, 46, 51]

21.94 (2.88-167.49)

21.16

0.0001

GAL-3 + HBME-1 + CK-19[14, 17, 29]

95.06 (25.17-359.08)

2.23

0.3280