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Table 3 Sensitivity, specificity, positive and negative predictive values (PPV and NPV) for CA125, HE4, and in combination with each other

From: Significance of HE4 estimation in comparison with CA125 in diagnosis of ovarian cancer and assessment of treatment response

 

Sensitivity

Specificity

PPV

NPV

HE4

90%

95%

93.1%

92.7%

CA125

83.3%

85%

80.7%

87.2%

HE4 + CA125

96.7%

80%

97%

80%