Table 2 Main results of pooled odds ratios (ORs) with confidence interval (CI) in the meta-analysis

9

1.352 (1.088 1.681)

0.000

0.00

1.354 (1.085 1.688)

0.001

0.007

1.017 (0.932 1.109)

0.592

0.712

3

1.240 (0.927 1.658)

0.002

0.148

1.184 (0.913 1.536)

0.006

0.203

1.041 (0.938 1.155)

0.278

0.448

3

1.758 (1.097 2.819)

0.373

0.019

1.800 (0.969 3.342)

0.196

0.063

0.955 (0.680 1.341)

0.575

0.791

2

1.476 (1.110 1.962)

0.554

0.007

1.586 (1.105 2.276)

0.256

0.012

0.962 (0.802 1.154)

0.655

0.677

5

1.225 (0.967 1.551)

0.009

0.093

1.233 (0.969 1.570)

0.88

0.088

1.017 (0.924 1.120)

0.382

0.728

3

1.854 (1.338 2.569)

0.958

0.000

1.806 (1.310 2.491)

0.896

0.000

1.013 (0.823 1.247)

0.678

0.900

No. of studies

OR (95% CI)

Ph

P

OR (95% CI)

Ph

P

OR (95% CI)

Ph

P

Lys/Lys vs Gln/Gln + Gln/Lys (dominant model)

Gln/Gln vs Gln/Lys + Lys/Lys (recessive model)

Gln allele vs Lys allele

9

0.945 (0.867 1.029)

0.397

0.194

1.362 (1.099 1.688)

0.18

0.18

1.109 (1.013 1.214)

0.019

0.024

3

0.940 (0.814 1.085)

0.086

0.397

1.219 (0.934 1.591)

0.002

0.145

1.097 (0.960 1.254)

0.003

0.175

3

0.890 (0.649 1.220)

0.948

0.468

1.781 (1.057 3.002)

0.241

0.030

1.258 (1.001 1.579)

0.546

0.049

2

0.954 (0.803 1.133)

0.846

0.590

1.489 (1.130 1.962)

0.357

0.005

1.123 (0.989 1.275)

0.996

0.073

5

0.962 (0.865 1.070)

0.264

0.480

1.239 (0.982 1.563)

0.003

0.071

1.078 (0.971 1.197)

0.021

0.160

3

0.874 (0.718 1.065)

0.655

0.183

1.824 (1.343 2.477)

0.956

0.000

1.233 (1.067 1.423)

0.749

0CPA004