|
Clinicopathologic characteristics
|
n
|
Nuclear CARM1 expression
|
P *
|
|---|
|
Negative or low expression (IHC score < 80)
|
High or over expression (IHC score f ≥ 80)
|
|---|
|
Age(y)
| | | | |
|
≤40
|
53
|
16 (30.2)
|
37 (69.8)
|
0.002
|
|
>40
|
194
|
105 (54.1)
|
89 (45.9)
| |
|
Tumor size
| | | | |
|
≤2 cm
|
125
|
65 (52.0)
|
60 (48.0)
|
0.338
|
|
>2 cm
|
122
|
56 (45.9)
|
66 (54.1)
| |
|
Tumor number
| | | | |
|
1
|
234
|
121 (51.7)
|
113 (48.3)
|
<0.001
|
|
≥2
|
13
|
0 (0)
|
13 (100.0)
| |
|
Grade
| | | | |
|
I&II
|
181
|
96 (53.0)
|
85 (47.0)
|
0.035
|
|
III
|
66
|
25 (37.9)
|
41 (62.1)
| |
|
Lymph node metastasis
| | | | |
|
N0
|
127
|
56 (44.1)
|
71 (55.9)
|
0.113
|
|
N1, N2,N3
|
120
|
65 (54.2)
|
55 (45.8)
| |
|
TNM stage
| | | | |
|
I
|
74
|
36 (48.6)
|
38 (51.4)
|
0.886
|
|
II
|
111
|
53 (47.7)
|
58 (52.3)
| |
|
III
|
62
|
32 (51.6)
|
30 (48.4)
| |
|
ER
| | | | |
|
negative
|
90
|
35 (38.9)
|
55 (61.1)
|
0.016
|
|
positive
|
157
|
86 (54.8)
|
71 (45.2)
| |
|
PR
| | | | |
|
negative
|
136
|
56 (41.2)
|
80 (58.8)
|
0.007
|
|
positive
|
111
|
65 (58.6)
|
46 (41.4)
| |
|
HER2
| | | | |
|
negative
|
206
|
107 (51.9)
|
99 (48.1)
|
0.037
|
|
positive
|
41
|
14 (34.1)
|
27 (65.9)
| |
|
Expression of Ki67
| | | | |
|
low (≤10%)
|
55
|
35 (63.6)
|
20 (36.4)
|
0.014
|
|
high (>10%)
|
192
|
86 (44.8)
|
106 (55.2)
| |
|
Expression of P53
| | | | |
|
low
|
95
|
57 (60.0)
|
38 (40.0)
|
0.006
|
|
high
|
152
|
64 (42.1)
|
88 (57.9)
| |
- * P value is the result of x2 test in the same factor, and < 0.05 is considered statistically significant.
