|
Clinicopathologic characteristics
|
n
|
Cytoplasmic CARM1 expression
|
P*
|
|---|
|
Negative or low expression (IHC score < 80)
|
High or over expression (IHC score ≥ 80)
|
|---|
|
Age(y)
| | | | |
|
≤40
|
53
|
16 (30.2)
|
37 (69.8)
|
0.041
|
|
>40
|
194
|
89 (45.9)
|
105 (54.1)
| |
|
Tumor size
| | | | |
|
≤2 cm
|
125
|
57 (45.6)
|
68 (54.4)
|
0.320
|
|
>2 cm
|
122
|
48 (39.3)
|
74 (60.7)
| |
|
Tumor number
| | | | |
|
1
|
234
|
101 (43.2)
|
133 (56.8)
|
0.379
|
|
≥2
|
13
|
4 (30.8)
|
9 (69.2)
| |
|
Grade
| | | | |
|
I&II
|
181
|
85 (47.0)
|
96 (53.0)
|
0.019
|
|
III
|
66
|
20 (30.3)
|
46 (69.7)
| |
|
Lymph node metastasis
| | | | |
|
N0
|
127
|
48 (37.8)
|
79 (62.2)
|
0.123
|
|
N1, N2,N3
|
120
|
57 (47.5)
|
63 (52.5)
| |
|
TNM stage
| | | | |
|
I
|
74
|
30 (40.5)
|
44 (59.5)
|
0.384
|
|
II
|
111
|
44 (39.6)
|
67 (60.4)
| |
|
III
|
62
|
31 (50.0)
|
31 (50.0)
| |
|
ER
| | | | |
|
negative
|
90
|
28 (31.1)
|
62 (68.9)
|
0.006
|
|
positive
|
157
|
77 (49.0)
|
80 (51.0)
| |
|
PR
| | | | |
|
negative
|
136
|
50 (36.8)
|
86 (63.2)
|
0.043
|
|
positive
|
111
|
55 (49.5)
|
56 (50.5)
| |
|
HER2
| | | | |
|
negative
|
206
|
93 (45.1)
|
113 (54.9)
|
0.060
|
|
positive
|
41
|
12 (29.3)
|
29 (70.7)
| |
|
Expression of K-i67
| | | | |
|
low (≤10%)
|
55
|
31 (56.4)
|
24 (43.6)
|
0.018
|
|
high (>10%)
|
192
|
74 (38.5)
|
118 (61.5)
| |
|
Expression of P53
| | | | |
|
low
|
95
|
45 (47.4)
|
50 (53.6)
|
0.222
|
|
high
|
152
|
60 (39.5)
|
92 (60.5)
| |
- * P value is the result of χ2 test in the same factor, and < 0.05 is considered statistically significant.
