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Table 3 Correlation between nuclear, cytoplasmic CARM1 expression and molecular subtypes of breast cancer patients

From: Overexpression of CARM1 in breast cancer is correlated with poorly characterized clinicopathologic parameters and molecular subtypes

Molecular subtypes

n

Nuclear CARM1 expression

P*

Cytoplasmic CARM1 expression

P *

Negative or low expression (IHC score < 80)

High or over expression (IHC score ≥ 80)

Negative or low expression (IHC score < 80)

High or over expression (IHC score ≥ 80)

Lumina A

121

71 (58.7)

50 (41.3)

0.019

60 (49.6)

61 (50.4)

0.066

Luminal B

47

19 (40.4)

28 (59.6)

 

19 (40.4)

28 (59.6)

 

HER2 type

23

7 (30.4)

16 (69.6)

 

5 (21.7)

18 (78.3)

 

triple negative

56

24 (42.9)

32 (57.1)

 

21 (37.5)

35 (62.5)

 
  1. * P value is the result of x2 test in the same factor, and < 0.05 is considered statistically significant.