Overexpression of CARM1 in breast cancer is correlated with poorly characterized clinicopathologic parameters and molecular subtypes

Table 3 Correlation between nuclear, cytoplasmic CARM1 expression and molecular subtypes of breast cancer patients

Molecular subtypes	n	Nuclear CARM1 expression		P*	Cytoplasmic CARM1 expression		P *
Molecular subtypes	n	Negative or low expression (IHC score < 80)	High or over expression (IHC score ≥ 80)	P*	Negative or low expression (IHC score < 80)	High or over expression (IHC score ≥ 80)	P *
Lumina A	121	71 (58.7)	50 (41.3)	0.019	60 (49.6)	61 (50.4)	0.066
Luminal B	47	19 (40.4)	28 (59.6)		19 (40.4)	28 (59.6)
HER2 type	23	7 (30.4)	16 (69.6)		5 (21.7)	18 (78.3)
triple negative	56	24 (42.9)	32 (57.1)		21 (37.5)	35 (62.5)

* P value is the result of x² test in the same factor, and < 0.05 is considered statistically significant.

ISSN: 1746-1596