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Table 4 STAT5 siRNA induced the apoptosis and suppressed invasion and metastasis of Eca-109

From: Effect of STAT5 silenced by siRNA on proliferation apoptosis and invasion of esophageal carcinoma cell line Eca-109

Group

Transfected vector

The cell apoptosis rate (%)

The average amount of cells per field

STAT5 siRNA

pRNAT-U6.1/Neo -siSTAT5

13.38 ± 1.87*

24.2 ± 5.1*

siRNA control

pRNAT-U6.1/Neo-siCon

4.76 ± 0.69

65.2 ± 10.4

The blank control

-

4.49 ± 0.73

71.9 ± 12.4

  1. The average apoptosis rate of Eca-109 cell transfected with STAT5 siRNA was significantly increased (*p < 0.05), The average amount of cells penetrating Matrigel was significantly suppressed (*p < 0.05).
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Diagnostic Pathology

ISSN: 1746-1596

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