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Table 3 Effect of hydroalcholic extract of N. sativa on the number of islets and the number of islet cells and islets diameter (μm) in pancreatic tissues in rats

From: RETRACTED ARTICLE: Protective and antidiabetic effects of extract from Nigella sativa on blood glucose concentrations against streptozotocin (STZ)-induced diabetic in rats: an experimental study with histopathological evaluation

Groups

Treatment groups*

Islets

Cells

Islets diameter (μm)

 1

Control

19.2 ± 4.9 d

120.4 ± 24.6 d

102.8 ± 11.8 d

 2

STZ

5 ± 1.4 a

42 ± 7.3 a

51.8 ± 16.3 a

 3

STZ+ NS 5 mg/kg b.w

13.6 ± 4.5 g e

85.6 ± 19.4 c e

84.4 ± 21.5 g f

 4

STZ+ NS 10 mg/kg b.w

6 ± 1.5 a h

47.6 ± 14.1 a h

63.4 ± 13.5 b h

 5

STZ+ NS 20 mg/kg b.w

5.4 ± 1.1 a h

49.2 ± 14.1 a h

57.2 ± 12 b h

  1. * Values are means ± SD (n5). a p 0.001 comparison to control; b p 0.01 comparison to control; c p 0.05 comparison to control; d p 0.001 comparison to STZ; e p 0.01 comparison to STZ; f p 0.05 comparison to STZ; g not significant comparison to control; h not significant comparison to STZ. The data were analyzed using One-way-ANOVA analysis and Tukey’s post hoc test.