RETRACTED ARTICLE: Protective and antidiabetic effects of extract from Nigella sativa on blood glucose concentrations against streptozotocin (STZ)-induced diabetic in rats: an experimental study with histopathological evaluation

Diagnostic Pathology

Table 3 Effect of hydroalcholic extract of N. sativa on the number of islets and the number of islet cells and islets diameter (μm) in pancreatic tissues in rats

Groups	Treatment groups*	Islets	Cells	Islets diameter (μm)
1	Control	19.2 ± 4.9 ^d	120.4 ± 24.6 ^d	102.8 ± 11.8 ^d
2	STZ	5 ± 1.4 ^a	42 ± 7.3 ^a	51.8 ± 16.3 ^a
3	STZ+ NS 5 mg/kg b.w	13.6 ± 4.5 ^{g e}	85.6 ± 19.4 ^{c e}	84.4 ± 21.5 ^{g f}
4	STZ+ NS 10 mg/kg b.w	6 ± 1.5 ^{a h}	47.6 ± 14.1 ^{a h}	63.4 ± 13.5 ^{b h}
5	STZ+ NS 20 mg/kg b.w	5.4 ± 1.1 ^{a h}	49.2 ± 14.1 ^{a h}	57.2 ± 12 ^{b h}

* Values are means ± SD (n5). ^a p 0.001 comparison to control; ^b p 0.01 comparison to control; ^c p 0.05 comparison to control; ^d p 0.001 comparison to STZ; ^e p 0.01 comparison to STZ; ^f p 0.05 comparison to STZ; ^g not significant comparison to control; ^h not significant comparison to STZ. The data were analyzed using One-way-ANOVA analysis and Tukey’s post hoc test.