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Table 1 Expression of CyclinD1 in the tissue of endometrial lesions

From: CyclinD1, a prominent prognostic marker for endometrial diseases

Pathological type

Cases assessed

CyclinD1

+

-

Positive Rate%*

Simple hyperplasia

27

8

19

30%

Atypical complex hyperplasia

41

20

21

49%

Endometrioid carcinoma

103

54

49

52%

Endometrial serous carcinoma

21

8

13

38%

Clear cell carcinoma

9

6

3

67%

  1. *: Grade and score by the intensity of immunoreactivity staining: 0 point for absent, 1 point for weak, 2 points for moderate and 3 points for strong; then grade by the extent of tissue staining: 0 point for no positive staining cells, 1 point for positive ratio <25%, 2 points for 25%-49%, 3 points for 50%-79% and 4 points for ≥ 80%. Finally, multiply the two score systems: ≤3 points for negative, >3 points for positive.