Association between the hOGG1 Ser326Cys polymorphism and lung cancer susceptibility: a meta-analysis based on 22,475 subjects

Table 1 Main characteristics of these studies included in this meta-analysis

First author [Inference]	Year	Country	Ethnicity	Control source	Cases			Controls			P _HWE
First author [Inference]	Year	Country	Ethnicity	Control source	Ser/Ser	Ser/Cys	Cys/Cys	Ser/Ser	Ser/Cys	Cys/Cys	P _HWE
Kohno	1998	Japan	Asian	PB	16	19	10	15	20	7	0.93
Le Marchand ^a	2002	USA	Caucasian	PB	78	39	9	98	53	8	0.81
Le Marchand ^b	2002	USA	Asian	PB	30	40	27	50	74	26	0.88
Lan	2004	China	Asian	PB	37	61	20	51	43	15	0.23
Vogel	2004	Denmark	Caucasian	PB	149	93	14	159	91	19	0.24
Loft	2006	Denmark	Caucasian	PB	144	93	14	154	88	19	0.20
Matullo	2006	Italy	Caucasian	PB	66	46	4	673	371	50	0.90
Sorensen	2006	Denmark	Caucasian	PB	254	155	22	479	284	33	0.26
Zienolddiny	2006	Italy	Caucasian	PB	182	100	44	194	117	75	0.01
Hatt	2008	Denmark	Caucasian	PB	92	58	8	93	59	12	0.54
Karahalil	2008	Turkey	Caucasian	PB	86	65	14	115	106	29	0.55
Okasaka	2009	Japan	Asian	PB	117	257	141	250	544	236	0.07
Li	2011	China	Asian	PB	83	208	164	60	219	164	0.33
Qian	2011	China	Asian	PB	100	288	193	125	291	185	0.59
Sugimura	1999	Japan	Asian	HB	85	115	41	63	107	27	0.08
Wikman	2000	Germany	Caucasian	HB	68	32	5	60	43	2	0.07
Ito	2002	Japan	Asian	HB	40	71	27	68	118	54	0.84
Sunaga	2002	Japan	Asian	HB	54	106	38	50	66	36	0.13
Park	2004	USA	Caucasian	HB	101	65	13	255	87	8	0.86
Hung	2005	European	Caucasian	HB	1401	661	93	1368	716	79	0.22
Liang	2005	China	Asian	HB	27	132	68	28	123	76	0.04
Wang	2005	China	Asian	HB	49	51	24	45	70	13	0.06
Kohno	2006	Japan	Asian	HB	285	544	268	123	190	81	0.63
De Ruyck	2007	Belgium	Caucasian	HB	74	33	3	60	46	4	0.18
Chang	2009	China	Asian	HB	142	518	436	154	482	361	0.74
Gao	2009	China	Asian	HB	27	35	24	30	49	11	0.19
Miyaishi	2009	Japan	Asian	HB	27	55	26	39	54	28	0.27
Liu	2010	China	Asian	HB	68	158	132	110	294	312	0.01
Janik	2011	Poland	Caucasian	HB	48	24	16	57	21	1	0.54
Kohno	2011	Japan	Asian	HB	115	162	100	98	164	63	0.70

^a,b Two different ethnicity studies in one publication. PB Population-Based Study, HB Hospital-Based Study, P_HWE P value of Hardy–Weinberg Equilibrium.

ISSN: 1746-1596