The expression of V-ATPase is associated with drug resistance and pathology of non-small-cell lung cancer

Diagnostic Pathology

Table 5 The correlation of V-ATPase expression with drug sensitivity (resistance) in lung adenocarcinoma

V-ATPase	Cyclophosphamide					Gemcitabine					Doxorubicin					Paclitaxel					Cisplatin
V-ATPase	R	LS	MS	HS	p value	R	LS	MS	HS	p value	R	LS	MS	HS	p value	R	LS	MS	HS	p value	R	LS	MS	HS	p value
_	0	9	4	1	χ² = 20.68	0	2	8	4	χ² = 21.45	0	1	6	7	χ² = 17.47	1	0	2	11	χ² = 15.12	2	2	6	4	χ² = 21.04
+	10	19	2	0	p = 0.002	3	6	20	2	p = 0.002	13	6	7	5	p = 0.008	1	0	5	25	p = 0.004	5	10	11	7	p = 0.002
++	4	0	0	0	rs = −0.584	2	2	0	0	rs = −0.512	2	2	0	0	rs = −0.544	2	0	2	0	rs = −0.269	4	0	0	0	rs = −0.306

R: Resistance; LS: Low sensitivity; MS: Moderate sensitivity; HS: High sensitivity.

ISSN: 1746-1596