Skip to main content

Table 1 Clinical features of 11 cases of inflammatory myofibroblastic tumor with RANBP2-ALK gene fusion

From: Inflammatory myofibroblastic tumor with RANBP2 and ALKgene rearrangement: a report of two cases and literature review

Case

Author

Age

Sex

Anatomic site(s)

Size (cm)

Treatment

Follow-up

1

Ma [5] (2003)

7 y

Male

Unspecified abdominal mass

NA

SE + CT

Recurred 5 weeks later after first resection. A re-excision was performed. Five months later, the tumor recurred again and was re-excised.

2

7 m

Male

Mesentery and omentum

11

SE

Recurred 8 months later after first resection. A re-excision was performed.

3

Patel [7] (2007)

2 y

Male

Retroperitoneal abdominal mass

10

SE

No evidence of recurrence with 3 years of follow-up.

4

Chen [8] (2008)

34 y

Male

Liver

8

SE

Recurred 5 months later after resection. Died of the disease approximately 2 weeks after discovery of the recurrence.

5

Butrynski [9] (2010)

44 y

Male

Omentum

NA

SE + CT + ALKi

Hepatic, peripancreatic, and perirectal masses recurred 1 year later after resection. Subsequent exploratory laparotomy with maximal debulking was performed.

6

Marino-Enriquez [10] (2011)

41 y

Male

Omentum

26

SE + CT + ALKi

Multifocal local recurrence and liver metastases. Alive with no evidence of disease for 40 months.

7

6 y

Male

Omentum and Mesentery

14

SE

NA

8

39 y

Male

Mesentery of the small bowel

14

SE

NA

9

Kozu [11] (2013)

57 y

Male

Pluera or chest wall

NA

ALKi

NA

10

Present cases (2013)

19 y

Female

Mesentery of the small bowel

19

SE

Recurred 9 weeks later after resection. Died of the disease 3 weeks later after discovery of the recurrence.

11

 

39 y

Male

Mesentery of the colon

15

SE + CT

Recurred 4 months later after resection. Alive with disease for 12 months.

  1. SE surgical excision, CT chemotherapy, ALKi ALK inhibitor, NA data not available.