Immunophenotypic features and t(14;18) (q32;q21) translocation of Chinese follicular lymphomas helps to distinguish subgroups

Table 3 CD10, BCL6 and MUM1 protein expression the FL subgroups

FL grading	CD10 positive		BCL6 positive		MUM1 positive
	n/N (%)	P	n/N (%)	P	n/N (%)	P
FL1	40/42 (95.2)	1.000^#	33/42 (78.6)	0.151^#	3/40 (7.5)	0.376^#
FL2	18/19 (94.7)	1.000^#	18/19 (94.7)	0.151^#	3/19 (15.8)	0.376^#
FL3A	21/31 (67.7)	0.756^*	25/31 (80.6)	1.000^#	11/29 (37.9)	0.032 ^*
FL3B	14/22 (63.6)	0.756^*	17/22 (77.3)	1.000^#	15/22 (68.2)	0.032 ^*
FL1-2	58/61 (95.1)	< 0.001 ^*	51/61 (83.6)	0.549^*	6/59 (10.2)	< 0.001 ^*
FL3	35/53 (66.0)	< 0.001 ^*	42/53 (79.2)	0.549^*	26/51 (51.0)	< 0.001 ^*
FL1-2	58/61 (95.1)	0.001 ^#	51/61 (83.6)	0.723^*	6/59 (10.2)	0.002 ^*
FL3A	21/31 (67.7)	0.001 ^#	25/31 (80.6)	0.723^*	11/29 (37.9)	0.002 ^*
FL1-3A	79/92 (85.9)	0.028 ^#	76/92 (82.6)	0.550^#	17/88 (19.3)	< 0.001 ^*
FL3B	14/22 (63.6)	0.028 ^#	17/22 (77.3)	0.550^#	15/22 (68.2)	< 0.001 ^*
Total	93/114 (81.6)		93/114 (81.6)		32/110 (29.1)

^*Pearson’s Chi-square test. ^#Fisher’s exact test. Bold text indicates significant P value. n/N (%), number positive/total number tested (percentage). FL, follicular lymphomas; FL1, FL grade 1; FL2, FL grade 2; FL3A, FL grade 3A; FL3B, FL grade 3B.

ISSN: 1746-1596