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Table 4 Copy number variations of mtDNA in early-stage gastric cancer — univariate associations with clinicopathological characteristics

From: Variable copy number of mitochondrial DNA (mtDNA) predicts worse prognosis in advanced gastric cancer patients

Characteristics

     Copy number <3.61

 

     Copy number >5.35

 

OR*(95% CI)

P

OR*(95% CI)

P

Male vs. Female

1.16 (0.11-12.13)

0.90

0.80 (0.06-11.30)

0.87

Age1

0.48 (0.05-4.65)

0.53

0.20 (0.02-2.39)

0.20

Tumor localization2

3.65 (0.91-14.64)

0.07

2.78 (0.59-13.0)

0.19

Tumor size3

0.80 (0.24-2.65)

0.71

0.56 (0.13-2.32)

0.42

Tumor invasion4

0.49 (0.16-1.49)

0.21

0.28 (0.08-0.99)

0.049

Lymph node metastasis

1.09 (0.17-6.85)

0.93

0.86 (0.10-7.51)

0.90

Survival status5

0.42 (0.07-2.43)

0.33

0.25 (0.03-2.32)

0.22

  1. *OR: odds ratio with 95% confidence interval; 1Age (per 10 years); 2Tumor localization (gastric cardia; gastric body; gastric antrum); 3Tumor size (≤3 cm; >3 cm and ≤5 cm; >5 cm); 4Tumor invasion (T1; T2; T3; T4); 5Survival status (Alive vs. Dead). The cases with 3.61-5.35 mtDNA copies were used as reference.