Alveolar-capillary permeability by Evan’s blue method. **p < 0.01 for the HE groups between AQP5 −/− and wildtype vs. HR and controls; &&p < 0.01 for the HR AQP5 −/− vs. HE and controls; &p < 0.05 for the HR wildtype vs. HE and controls. n = 3 in each group. Values are given as the mean ± SEM.