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Table 5 Correlation of EDNRB mRNA expression and clinicopathological parameters of colorectal cancer samples*

From: Hypermethylation of EDNRB promoter contributes to the risk of colorectal cancer

   

EDNRB expression relative to GAPDH

 

Characteristics

 

n

Mean

SD

SE

p value

Gender

Male

28

0.336

1.073

0.202

0.722

 

Female

14

0.250

0.480

0.130

 

Age (year)

≤60

16

0.221

0.444

0.111

0.836

 

>60

26

0.360

1.114

0.218

 

Stage

1/2

21

0.143

0.233

0.051

0.792

 

3/4

21

0.472

1.257

0.281

 

Lymph metastasis

Yes

21

0.457

1.266

0.276

0.95

 

No

21

0.158

0.238

0.052

 

Distant metastasis

Yes

8

0.781

1.996

0.706

0.741

 

No

34

0.196

0.351

0.060

 

CEA

≥5.0 ng/ml

15

0.121

0.156

0.040

0.723

 

<5.0 ng/ml

27

0.411

1.127

0.217

 

CA19-9

≥37U/ml

9

0.102

0.153

0.051

0.526

 

<37U/ml

33

0.364

1.023

0.178

 

Tumor location

Colon

26

0.428

1.145

0.225

0.351

 

Rectum

16

0.112

0.156

0.039

 

Differentiation

Poor

10

0.719

1.779

0.558

0.494

 

Moderate

32

0.179

0.341

0.062

 
 

Well

0

/

/

/

 

Tumor size

<5 cm

28

0.386

1.102

0.208

0.968

 

≥5 cm

14

0.151

0.248

0.066

 

Histological classification

Adenocarcinoma

40

0.315

0.935

0.148

0.455

 

Mucinous adenocarcinoma

2

0.162

0.157

0.111

 
 

Undifferentiated carcinoma

0

/

/

/

 
  1. *: SD denotes standard deviation and SE denotes standard error.