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Table 5 Correlation of EDNRB mRNA expression and clinicopathological parameters of colorectal cancer samples*

From: Hypermethylation of EDNRB promoter contributes to the risk of colorectal cancer

    EDNRB expression relative to GAPDH  
Characteristics   n Mean SD SE p value
Gender Male 28 0.336 1.073 0.202 0.722
  Female 14 0.250 0.480 0.130  
Age (year) ≤60 16 0.221 0.444 0.111 0.836
  >60 26 0.360 1.114 0.218  
Stage 1/2 21 0.143 0.233 0.051 0.792
  3/4 21 0.472 1.257 0.281  
Lymph metastasis Yes 21 0.457 1.266 0.276 0.95
  No 21 0.158 0.238 0.052  
Distant metastasis Yes 8 0.781 1.996 0.706 0.741
  No 34 0.196 0.351 0.060  
CEA ≥5.0 ng/ml 15 0.121 0.156 0.040 0.723
  <5.0 ng/ml 27 0.411 1.127 0.217  
CA19-9 ≥37U/ml 9 0.102 0.153 0.051 0.526
  <37U/ml 33 0.364 1.023 0.178  
Tumor location Colon 26 0.428 1.145 0.225 0.351
  Rectum 16 0.112 0.156 0.039  
Differentiation Poor 10 0.719 1.779 0.558 0.494
  Moderate 32 0.179 0.341 0.062  
  Well 0 / / /  
Tumor size <5 cm 28 0.386 1.102 0.208 0.968
  ≥5 cm 14 0.151 0.248 0.066  
Histological classification Adenocarcinoma 40 0.315 0.935 0.148 0.455
  Mucinous adenocarcinoma 2 0.162 0.157 0.111  
  Undifferentiated carcinoma 0 / / /  
  1. *: SD denotes standard deviation and SE denotes standard error.