From: Hypermethylation of EDNRB promoter contributes to the risk of colorectal cancer
EDNRB expression relative to GAPDH | ||||||
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Characteristics | n | Mean | SD | SE | p value | |
Gender | Male | 28 | 0.336 | 1.073 | 0.202 | 0.722 |
Female | 14 | 0.250 | 0.480 | 0.130 | ||
Age (year) | ≤60 | 16 | 0.221 | 0.444 | 0.111 | 0.836 |
>60 | 26 | 0.360 | 1.114 | 0.218 | ||
Stage | 1/2 | 21 | 0.143 | 0.233 | 0.051 | 0.792 |
3/4 | 21 | 0.472 | 1.257 | 0.281 | ||
Lymph metastasis | Yes | 21 | 0.457 | 1.266 | 0.276 | 0.95 |
No | 21 | 0.158 | 0.238 | 0.052 | ||
Distant metastasis | Yes | 8 | 0.781 | 1.996 | 0.706 | 0.741 |
No | 34 | 0.196 | 0.351 | 0.060 | ||
CEA | ≥5.0 ng/ml | 15 | 0.121 | 0.156 | 0.040 | 0.723 |
<5.0 ng/ml | 27 | 0.411 | 1.127 | 0.217 | ||
CA19-9 | ≥37U/ml | 9 | 0.102 | 0.153 | 0.051 | 0.526 |
<37U/ml | 33 | 0.364 | 1.023 | 0.178 | ||
Tumor location | Colon | 26 | 0.428 | 1.145 | 0.225 | 0.351 |
Rectum | 16 | 0.112 | 0.156 | 0.039 | ||
Differentiation | Poor | 10 | 0.719 | 1.779 | 0.558 | 0.494 |
Moderate | 32 | 0.179 | 0.341 | 0.062 | ||
Well | 0 | / | / | / | ||
Tumor size | <5 cm | 28 | 0.386 | 1.102 | 0.208 | 0.968 |
≥5 cm | 14 | 0.151 | 0.248 | 0.066 | ||
Histological classification | Adenocarcinoma | 40 | 0.315 | 0.935 | 0.148 | 0.455 |
Mucinous adenocarcinoma | 2 | 0.162 | 0.157 | 0.111 | ||
Undifferentiated carcinoma | 0 | / | / | / |