expression of PRMT5 is seen throughout the entire spectrum of lung tumors; representative examples of adenocarcinoma
, squamous cell carcinoma
, large cell neuroendocrine carcinoma
and typical carcinoid tumor
; no PRMT5 is observed in normal alveolar parenchyma
illustrate low and high cytoplasmic expression, respectively; panels
illustrate low and high nuclear expression, respectively; immunohistochemistry; original magnification ×400.