Figure 3
From: Cellular localization of protein arginine methyltransferase-5 correlates with grade of lung tumors
Cytoplasmic (a-e) and nuclear (a, c and e) expression of PRMT5 is seen throughout the entire spectrum of lung tumors; representative examples of adenocarcinoma (a) , squamous cell carcinoma (b-c) , large cell neuroendocrine carcinoma (d) and typical carcinoid tumor (e) ; no PRMT5 is observed in normal alveolar parenchyma (f) Panels (b) and (d) illustrate low and high cytoplasmic expression, respectively; panels (a) and (e) illustrate low and high nuclear expression, respectively; immunohistochemistry; original magnification ×400.