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Table 2 PRMT5 expression in NSCLC

From: Cellular localization of protein arginine methyltransferase-5 correlates with grade of lung tumors

  

Cytoplasmic high PRMT5, n (%)

P

Nuclear high PRMT5, n (%)

P

Na

Age

≤60 years (n = 65)

11 (5.4)

0.36

22 (10.8)

0.55

204

>60 years (n = 139)

30 (14.7)

55 (27.0)

Gender

Female (n = 53)

9 (4.1)

0.79

19 (8.8)

0.25

217

Male (n = 164)

35 (16.1)

62 (28.6)

Size

≤3 cm (n = 74)

9 (6.3)

0.09

31 (21.8)

0.35

142

>3 cm (n = 68)

18 (12.7)

22 (15.5)

Stage

I (n = 81)

14 (9.9)

0.63

32 (22.7)

0.19

141

II-IV (n = 60)

13 (9.2)

21 (14.9)

Grade

WD, MD (n = 55)

7 (7.2)

0.01

20 (20.6)

0.98

97

PD (n = 42)

16 (16.5)

16 (16.5)

Histology

ADC (n = 113)

19 (8.3)

0.04

28 (12.2)

<0.001

229

SQC (n = 116)

28 (12.2)

59 (25.8)

Survival

Yes (n = 44)

9 (4.8)

0.37

14 (7.4)

0.54

189

 

No (n = 145)

30 (15.9)

 

57 (30.2)

  
  1. Abbreviations: Neg negative, N number of cases, WD well differentiated, MD moderately differentiated, PD poorly differentiated, ADC adenocarcinoma, SQC squamous cell carcinoma.
  2. aReflects total number of cases with available annotations.