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Table 2 PRMT5 expression in NSCLC

From: Cellular localization of protein arginine methyltransferase-5 correlates with grade of lung tumors

   Cytoplasmic high PRMT5, n (%) P Nuclear high PRMT5, n (%) P Na
Age ≤60 years (n = 65) 11 (5.4) 0.36 22 (10.8) 0.55 204
>60 years (n = 139) 30 (14.7) 55 (27.0)
Gender Female (n = 53) 9 (4.1) 0.79 19 (8.8) 0.25 217
Male (n = 164) 35 (16.1) 62 (28.6)
Size ≤3 cm (n = 74) 9 (6.3) 0.09 31 (21.8) 0.35 142
>3 cm (n = 68) 18 (12.7) 22 (15.5)
Stage I (n = 81) 14 (9.9) 0.63 32 (22.7) 0.19 141
II-IV (n = 60) 13 (9.2) 21 (14.9)
Grade WD, MD (n = 55) 7 (7.2) 0.01 20 (20.6) 0.98 97
PD (n = 42) 16 (16.5) 16 (16.5)
Histology ADC (n = 113) 19 (8.3) 0.04 28 (12.2) <0.001 229
SQC (n = 116) 28 (12.2) 59 (25.8)
Survival Yes (n = 44) 9 (4.8) 0.37 14 (7.4) 0.54 189
  No (n = 145) 30 (15.9)   57 (30.2)   
  1. Abbreviations: Neg negative, N number of cases, WD well differentiated, MD moderately differentiated, PD poorly differentiated, ADC adenocarcinoma, SQC squamous cell carcinoma.
  2. aReflects total number of cases with available annotations.