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Table 2 Expression of CLAUDIN-10, CLAUDIN-14, CLAUDIN-17 and clinic pathological characteristics in gastric cancer patients

From: The distinct expression patterns of claudin-10, -14, -17 and E-cadherin between adjacent non-neoplastic tissues and gastric cancer tissues

Item

n

CLAUDIN-10(+)

CLAUDIN-10(-)

P

n

CLAUDIN-14(+)

CLAUDIN-14(-)

P

n

CLAUDIN-17(+)

CLAUDIN-17(-)

P

Gastric cancer tissue

50

12

38

<0.01

50

29

21

<0.01

50

9

41

<0.01

Adjacent tissue

50

36

14

 

50

12

38

 

50

35

15

 

Gender

            

Male

34

8

28

0.664*

34

20

14

0.355*

34

7

27

0.475*

Female

16

4

12

 

16

9

7

 

16

2

14

 

Age(year)

            

≤60

26

7

19

1.000*

26

15

11

1.000*

26

4

22

0.677*

>60

24

5

19

 

24

14

10

 

24

5

19

 

Histological grade

            

Well –differentiated

14

4

10

1.000*

14

6

8

0.641*

14

3

11

1.000*

Moderately differentiated

25

7

18

 

25

15

10

 

25

5

20

 

Poor differentiated

11

1

10

 

11

8

3

 

11

1

10

 

Lymph node metastasis

            

+

24

3

21

<0.01

24

18

6

<0.05

24

2

22

<0.05

-

26

9

17

 

26

11

15

 

26

7

19

 

E-cadherin

            

+

16

9

7

<0.0

 

7

9

 

16

6

10

<0.01

-

 

3

 

1

16

22

12

<0.05

34

3

31

 

Ki67

  

31

         

+

 

5

  

34

9

8

 

17

4

13

0.633*

-

34

7

12

0.464*

  

13

  

5

28

 
   

26

    

1.000*

    
 

17

   

17

       
 

33

   

33

20

  

33

   
  1. *No statistical significance.