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Table 1 Clinicopathological features of patients with OSCs

From: P53, MAPK, topoisomerase II alpha and Ki67 immunohistochemical expression and KRAS/BRAF mutation in ovarian serous carcinomas

 

Low-grade

High-grade

P

(n = 11)

(n = 70)

Age at diagnosis, yrs, median (min-max)

52 (44–71)

63.5 (37–89)

0.028*

FIGO stage, n (%)

   

I-II

4 (36.4)

6 (8.6)

0.026

III-IV

7 (63.6)

64 (91.5)

Mitotic activity, median (min-max)

9 (1–12)

27 (13–65)

< 0.001*

Vascular invasion, n (%)

   

No

10 (90.9)

20 (28.6)

< 0.001

Yes

1 (9.1)

50 (71.4)

Residual tumor, n (%)

   

No

7 (63.6)

12 (17.1)

0.019

≤ 2 cm

1 (9.1)

14 (20.2)

≥ 2 cm

3 (27.3)

44 (62.9)

  1. *Based on Mann–Whitney U test.
  2. Based on χ2 test.