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Table 2 Immunohistochemical staining results of p53, MAPK, topoIIα and Ki67 expression in OSCs

From: P53, MAPK, topoisomerase II alpha and Ki67 immunohistochemical expression and KRAS/BRAF mutation in ovarian serous carcinomas

  Low-grade High-grade P
(n = 11) (n = 70)
p53, n (%)    
negative 11 (100) 10 (14.3) < 0.001
positive 0 (0) 60 (85.7)  
MAPK, n (%)    
negative 4 (36.4) 58 (82.9) 0.003
positive 7 (63.6) 12 (17.1)  
topoII alpha, n (%)    
negative 7 (63.6) 13 (18.6) 0.001
positive 4 (36.4) 57 (81.4)  
Ki67, median (min-max) 19 (7–54) 56.5 (18–98) < 0.001*
  1. Based on χ2 test.
  2. *Based on Mann–Whitney U test.