Trichogerminoma, a rare cutaneous follicular neoplasm with indolent clinical course: report of two cases and review of literature

Table 1 Clinicopathological characteristics of trichogerminoma described in present and previous reports

Case no.	Author (year)	Diagnosis	Age (year)/ gender	Site	Immunoprofiles	Treatment	Outcome
1	Sau G (1992) [1]	TG	34/female	Scalp	NA	TSR	NED 6 years
2		TG	55/female	Back	NA	TSR	NED 11 years
3		TG	53/male	Right calf	NA	TSR	NED 9 years
4		TG	16/female	Right eye brow	NA	TSR	NA
5		TG	25/male	NA	NA	TSR	NED 8 years
6		TG	27/female	Forehead	NA	TSR	NED 7 years
7		TG	60/male	Right cheek	NA	TSR	NED 5.5 years
8		TG	53/male	Submental	NA	TSR	NED 6 years
9		TG	59/female	Left ear	NA	TSR	NED 6 years
10		TG	43/male	Abdomen	NA	TSR	NED 3 years
11		TG	73/male	Right breast	NA	TSR	NED 3 years
12		TG	73/male	Abdomen	NA	TSR/RT	Recur & metast to soft tissue LN & liver 4 months
13		TG	58/male	Right hip	NA	TSR	NED 2 years
14		TG	61/male	Left arm	NA	TSR	NED 1.5 years
15	Kazakov (2002) [2]	TG	41/male	Left eye	AE1/AE3 +, CK20 -	TSR	NED 6 months
16	Pozo (2005) [3]	TG	74/female	Face	AE1/AE3 +, CK20 -	TSR	NA
17	Tellchea (2009) [4]	TG	45/male	Scalp	AE1/AE3 +, CK5/6 zonal+	TSR	NED 10 years
18	Kim (2010) [5]	TG	79/female	Neck	AE1/AE3 +, CK5/6 zonal+	TSR	NED 6 months
19	Present case No.1	TG	78/male	Hip	AE1/AE3 +, CK5/6, Bcl-2 zonal+, CK20 -	TSR	NED 6 months
20	Present case No.2	TG	29/male	Right thigh	AE1/AE3 +, CK5/6, P63, Bcl-2 zonal+, CK20 -	TSR	NED 12 months

TG, trichogerminoma; NA, not available; NED, no evidence of disease; TSR, totally surgical resection; RT, radiotherapy.