Histological subtypes and characteristic structures of HPV-associated oropharyngeal carcinoma; study with Japanese cases

Table 1 Clinical features of oropharyngeal SCCs

	Total	%	HPV-OPC	%	nHPV-OPC	%	P value
	(n = 66)	%	(n = 31)		(n = 35)	%	P value
Sex
Male	44	66.7	21	47.7	23	52.3	NS
Female	22	33.3	10	45.5	12	54.5	NS
Age^a	66(37–90)		66.5( 43–87)		67.0(37–90)		NS
Tobacco^b
(-)	29	43.9	13	44.8	16	55.2	NS
(+)	37	56.1	18	48.6	19	51.4	NS
Alcohol^b
(-)	29	43.9	12	41.4	14	58.6	NS
(+)	37	56.1	19	51.4	21	48.6	NS
Site^c
Lat	50	75.6	27	54.0	23	46.0	NS
Ant	11	16.7	4	36.4	7	63.6
Post	3	4.5	0	0.0	3	100.0
Sup	2	3.2	0	0.0	2	100.0
Stage
I/II	11	16.7	6	54.5	5	45.5	NS
III/IV	55	83.3	25	45.5	30	54.5	NS

^aAge: mean and range in parenthesis are shown
^bTobacco and alcohol: (-), never; (+), ever and current
^cTumor site: Lat, lateral wall; Ant, anterior wall; Post, posterior wall; Sup, superior wall.